Antimalarial activity and phitochemical analysis from Suruhan (Peperomia pellucida) extract

Authors

  • Nurhayati Bialangi Jurusan Kimia
  • Moh Adam Mustapa Jurusan Farmasi
  • Yuszda K Salimi Jurusan Kimia
  • Ari Widiantoro Jurusan Kimia
  • Boima Situmeang Jurusan Analis Kimia

DOI:

https://doi.org/10.24114/jpkim.v8i3.5817

Abstract

Abstract. Infectious and parasitic diseases is one of various disease that the most common. Based on data from the World Health Organization (WHO) in 2011, infectious and parasitic diseases become the third largest cause of death in the world. One of the plants that have potential as an antimalarial is suruhan (Peperomia pellucida). The purpose of this study is to test antimalarial activity against Plasmodium falciparum and analysis photochemistry consituen from extract suruhan. Antimalarial activity test using Desjardin method. Extraction was done by using maceration wuth methanol as a solvent and fractionation using partition methods. Results of phytochemical screening revealed the presence of alkaloids, flavonoid, steroid, saponins and triterpenoid test results antimalarial activity fraction of n-hexane, ethyl acetate and water show IC50 values are 12.80, 2.90 and 10.74 mg/ mL respectively.Keyword: Peperomia pellucida, suruhan, antimalarial

Author Biographies

Nurhayati Bialangi, Jurusan Kimia

Fakultas MIPA, Universitas Negeri Gorontalo, Gorontalo

Moh Adam Mustapa, Jurusan Farmasi

Fakultas Olah Raga dan Kesehatan, Universitas Negeri Gorontalo

Yuszda K Salimi, Jurusan Kimia

Fakultas MIPA, Universitas Negeri Gorontalo, Gorontalo

Ari Widiantoro, Jurusan Kimia

Fakultas MIPA, Universitas Negeri Tanjungpura, Pontianak

Boima Situmeang, Jurusan Analis Kimia

Sekolah Tinggi Analis Kimia Cilegon, Banten

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